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Transcriptional Analysis of the Adeno-Associated Virus Integration Site

The nonpathogenic human adeno-associated virus type 2 (AAV-2) has adopted a unique mechanism to site-specifically integrate its genome into the human MBS85 gene, which is embedded in AAVS1 on chromosome 19. The fact that AAV has evolved to integrate into this ubiquitously transcribed region and that...

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Auteurs principaux: Dutheil, Nathalie, Henckaerts, Els, Kohlbrenner, Erik, Linden, R. Michael
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2009
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786763/
https://ncbi.nlm.nih.gov/pubmed/19759129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01754-09
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