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Hepatitis C Virus Causes Uncoupling of Mitotic Checkpoint and Chromosomal Polyploidy through the Rb Pathway

Hepatitis C virus (HCV) infection is associated with the development of hepatocellular carcinoma and probably also non-Hodgkin's B-cell lymphoma. The molecular mechanisms of HCV-associated carcinogenesis are unknown. Here we demonstrated that peripheral blood mononuclear cells obtained from hep...

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Detalhes bibliográficos
Main Authors: Machida, Keigo, Liu, Jian-Chang, McNamara, George, Levine, Alexandra, Duan, Lewei, Lai, Michael M. C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786750/
https://ncbi.nlm.nih.gov/pubmed/19793824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02643-08
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