Clade-Specific Evolution Mediated by HLA-B*57/5801 in Human Immunodeficiency Virus Type 1 Clade A1 p24

HLA-B*57-mediated selection pressure leads to a typical escape pathway in human immunodeficiency virus type 1 (HIV-1) CD8 epitopes such as TW10. Whether this T242N pathway is shared by all clades remains unknown. We therefore assessed the nature of HLA-B*57 selection in a large, observational Kenyan...

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Autors principals: McKinnon, Lyle R., Capina, Rupert, Peters, Harold, Mendoza, Mark, Kimani, Joshua, Wachihi, Charles, Kariri, Anthony, Kimani, Makobu, Richmond, Meika, Kiazyk, Sandy Koesters, Fowke, Keith R., Jaoko, Walter, Luo, Ma, Ball, T. Blake, Plummer, Francis A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2009
Matèries:
Genetic Diversity and Evolution
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786721/
https://ncbi.nlm.nih.gov/pubmed/19759140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01236-09
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