Clade-Specific Evolution Mediated by HLA-B*57/5801 in Human Immunodeficiency Virus Type 1 Clade A1 p24

HLA-B*57-mediated selection pressure leads to a typical escape pathway in human immunodeficiency virus type 1 (HIV-1) CD8 epitopes such as TW10. Whether this T242N pathway is shared by all clades remains unknown. We therefore assessed the nature of HLA-B*57 selection in a large, observational Kenyan...

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Hlavní autoři: McKinnon, Lyle R., Capina, Rupert, Peters, Harold, Mendoza, Mark, Kimani, Joshua, Wachihi, Charles, Kariri, Anthony, Kimani, Makobu, Richmond, Meika, Kiazyk, Sandy Koesters, Fowke, Keith R., Jaoko, Walter, Luo, Ma, Ball, T. Blake, Plummer, Francis A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2009
Témata:
Genetic Diversity and Evolution
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786721/
https://ncbi.nlm.nih.gov/pubmed/19759140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01236-09
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