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Control of Herpes Simplex Virus Replication Is Mediated through an Interferon Regulatory Factor 3-Dependent Pathway

The type I interferon (IFN) cascade is critical in controlling viral replication and pathogenesis. Recognition pathways triggered by viral infection rapidly induce the type I IFN cascade, often in an IFN regulatory factor 3 (IRF-3)-dependent fashion. This dependence predicts that loss of IRF-3 would...

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Detalhes bibliográficos
Main Authors: Menachery, Vineet D., Leib, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786705/
https://ncbi.nlm.nih.gov/pubmed/19759149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00888-09
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