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Metal-Responsive Transcription Factor 1 (MTF-1) Activity Is Regulated by a Nonconventional Nuclear Localization Signal and a Metal-Responsive Transactivation Domain

Metal-responsive transcription factor 1 (MTF-1) mediates both basal and heavy metal-induced transcription of metallothionein genes and also regulates other genes involved in the cell stress response and in metal homeostasis. In resting cells, MTF-1 localizes to both the cytoplasm and the nucleus but...

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Autors principals: Lindert, Uschi, Cramer, Mirjam, Meuli, Michael, Georgiev, Oleg, Schaffner, Walter
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786702/
https://ncbi.nlm.nih.gov/pubmed/19797083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00847-09
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