Malaria Ookinete Surface Protein-Based Vaccination via the Intranasal Route Completely Blocks Parasite Transmission in both Passive and Active Vaccination Regimens in a Rodent Model of Malaria Infection

Malaria vaccines based on ookinete surface proteins (OSPs) of the malaria parasites block oocyst development in feeding mosquitoes and hence disrupt the parasite life cycle and prevent the disease from being transmitted to other individuals. To investigate whether a noninvasive mucosal vaccination r...

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Detalhes bibliográficos
Main Authors: Arakawa, Takeshi, Tachibana, Mayumi, Miyata, Takeshi, Harakuni, Tetsuya, Kohama, Hideyasu, Matsumoto, Yasunobu, Tsuji, Naotoshi, Hisaeda, Hajime, Stowers, Anthony, Torii, Motomi, Tsuboi, Takafumi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Fungal and Parasitic Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786443/
https://ncbi.nlm.nih.gov/pubmed/19752035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00640-09
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