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Thermal Stabilization of Erwinia chrysanthemi Pectin Methylesterase A for Application in a Sugar Beet Pulp Biorefinery

Directed evolution approaches were used to construct a thermally stabilized variant of Erwinia chrysanthemi pectin methylesterase A. The final evolved enzyme has four amino acid substitutions that together confer a T(m) value that is approximately 11°C greater than that of the wild-type enzyme, whil...

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Autores principales: Chakiath, Chacko, Lyons, Margaret J., Kozak, Robert E., Laufer, Craig S.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786414/
https://ncbi.nlm.nih.gov/pubmed/19820151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.01010-09
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