New Small-Molecule Inhibitor Class Targeting Human Immunodeficiency Virus Type 1 Virion Maturation

A new small-molecule inhibitor class that targets virion maturation was identified from a human immunodeficiency virus type 1 (HIV-1) antiviral screen. PF-46396, a representative molecule, exhibits antiviral activity against HIV-1 laboratory strains and clinical isolates in T-cell lines and peripher...

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Detalhes bibliográficos
Main Authors: Blair, Wade S., Cao, Joan, Fok-Seang, Juin, Griffin, Paul, Isaacson, Jason, Jackson, R. Lynn, Murray, Edward, Patick, Amy K., Peng, Qinghai, Perros, Manos, Pickford, Chris, Wu, Hua, Butler, Scott L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786326/
https://ncbi.nlm.nih.gov/pubmed/19805571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00759-09
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