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Synthesis of a quinolone library from ynones

A library of 72 quinolones was synthesized from substituted anthranilic acids, using ynone intermediates. These masked β-dicarbonyl synthons allowed cyclization under milder conditions than previously reported quinolone syntheses.

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Ward, Timothy R., Turunen, Brandon J., Haack, Torsten, Neuenswander, Benjamin, Shadrick, William, Georg, Gunda I.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2009
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786061/
https://ncbi.nlm.nih.gov/pubmed/20161410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2009.09.024
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