Pulsatile stimulation determines timing and specificity of NF-kappa B-dependent transcription

The Nuclear Factor kappa B (NF-κB) transcription factor regulates cellular stress responses and the immune response to infection. NF-κB activation results in oscillations in nuclear NF-κB abundance. To define the function of these oscillations, we treated cells with repeated short pulses of tumor ne...

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Detalles Bibliográficos
Main Authors: Ashall, L., Horton, C.A., Nelson, D.E., Paszek, P., Harper, C.V., Sillitoe, K., Ryan, S., Spiller, D.G., Unitt, J.F., Broomhead, D.S., Kell, D.B., Rand, D.A., Sée, V., White, M.R.H.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785900/
https://ncbi.nlm.nih.gov/pubmed/19359585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1164860
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