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Pulsatile stimulation determines timing and specificity of NF-kappa B-dependent transcription
The Nuclear Factor kappa B (NF-κB) transcription factor regulates cellular stress responses and the immune response to infection. NF-κB activation results in oscillations in nuclear NF-κB abundance. To define the function of these oscillations, we treated cells with repeated short pulses of tumor ne...
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| Main Authors: | , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2785900/ https://ncbi.nlm.nih.gov/pubmed/19359585 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1164860 |
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