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Population robustness arising from cellular heterogeneity

Heterogeneity between individual cells is a common feature of dynamic cellular processes, including signaling, transcription, and cell fate; yet the overall tissue level physiological phenotype needs to be carefully controlled to avoid fluctuations. Here we show that in the NF-κB signaling system, t...

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Detalhes bibliográficos
Main Authors: Paszek, Pawel, Ryan, Sheila, Ashall, Louise, Sillitoe, Kate, Harper, Claire V., Spiller, David G., Rand, David A., White, Michael R. H.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2895068/
https://ncbi.nlm.nih.gov/pubmed/20534546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0913798107
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