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Abnormalities in brain structure and behavior in GSK-3alpha mutant mice

BACKGROUND: Glycogen synthase kinase-3 (GSK-3) is a widely expressed and highly conserved serine/threonine protein kinase encoded by two genes that generate two related proteins: GSK-3α and GSK-3β. Mice lacking a functional GSK-3α gene were engineered in our laboratory; they are viable and display i...

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Hlavní autoři: Kaidanovich-Beilin, Oksana, Lipina, Tatiana V, Takao, Keizo, van Eede, Matthijs, Hattori, Satoko, Laliberté, Christine, Khan, Mustafa, Okamoto, Kenichi, Chambers, John W, Fletcher, Paul J, MacAulay, Katrina, Doble, Bradley W, Henkelman, Mark, Miyakawa, Tsuyoshi, Roder, John, Woodgett, James R
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785804/
https://ncbi.nlm.nih.gov/pubmed/19925672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-6606-2-35
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