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Targeting glycogen synthase kinase-3 (GSK-3) in the treatment of Type 2 diabetes

BACKGROUND: In spite of its rather specific name, glycogen synthase kinase-3 (GSK-3) is an eclectic cellular regulator that modulates an array of processes from nuclear transcription, to neurological functions and metabolism. The enzyme is also a focal point for diverse signaling pathways that act t...

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Pubblicato in:Expert Opin Ther Targets
Autori principali: MacAulay, Katrina, Woodgett, James R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4485462/
https://ncbi.nlm.nih.gov/pubmed/18781825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/14728222.12.10.1265
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