Proteasome inhibition potentiates antitumor effects of photodynamic therapy in mice through induction of ER stress and unfolded protein response

Photodynamic therapy (PDT) is an approved therapeutic procedure that exerts cytotoxic activity towards tumor cells by inducing production of reactive oxygen species such as singlet oxygen. PDT leads to oxidative damage of cellular macromolecules, including numerous proteins that undergo multiple mod...

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Hauptverfasser: Szokalska, Angelika, Makowski, Marcin, Nowis, Dominika, Wilczyński, Grzegorz M., Kujawa, Marek, Wójcik, Cezary, Młynarczuk-Biały, Izabela, Salwa, Pawel, Bil, Jacek, Janowska, Sylwia, Agostinis, Patrizia, Verfaillie, Tom, Bugajski, Marek, Gietka, Jan, Issat, Tadeusz, Głodkowska, Eliza, Mrówka, Piotr, Stoklosa, Tomasz, Hamblin, Michael R, Mróz, Paweł, Jakóbisiak, Marek, Golab, Jakub
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785802/
https://ncbi.nlm.nih.gov/pubmed/19435917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-3439
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