Berberine Inhibits Metastasis of Nasopharyngeal Carcinoma 5-8F Cells by Targeting Rho Kinase-mediated Ezrin Phosphorylation at Threonine 567

Ezrin is highly expressed in metastatic tumors and is involved in filopodia formation as well as promotion of tumor metastasis. Thus, Ezrin may serve as a potential target for anti-metastatic therapy. This study demonstrates that berberine reduces filopodia formation of a nasopharyngeal carcinoma (N...

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Detalhes bibliográficos
Main Authors: Tang, Faqing, Wang, Dongsheng, Duan, Chaojun, Huang, Damao, Wu, Yuan, Chen, Yu, Wang, Weiwei, Xie, Chunlei, Meng, Jingjing, Wang, Lei, Wu, Bin, Liu, Shujin, Tian, Daofa, Zhu, Feng, He, Zhiwei, Deng, Fuliang, Cao, Ya
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Mechanisms of Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785675/
https://ncbi.nlm.nih.gov/pubmed/19651779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.033795
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