N,N′-Dinitrosopiperazine-mediated Ezrin Protein Phosphorylation via Activation of Rho Kinase and Protein Kinase C Is Involved in Metastasis of Nasopharyngeal Carcinoma 6-10B Cells

N,N′-Dinitrosopiperazine (DNP) is a carcinogen for nasopharyngeal carcinoma (NPC), which shows organ specificity to nasopharyngeal epithelium. Herein, we demonstrate that DNP induces fiber formation of NPC cells (6-10B) and also increases invasion and motility of 6-10B cells. DNP-mediated NPC metast...

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Detalhes bibliográficos
Main Authors: Tang, Faqing, Zou, Feiyan, Peng, Zhengke, Huang, Damao, Wu, Yuan, Chen, Yu, Duan, Chaojun, Cao, Ya, Mei, Wenhua, Tang, Xiaowei, Dong, Zigang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196127/
https://ncbi.nlm.nih.gov/pubmed/21878630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.259234
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