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Suppression of Tumor Angiogenesis by Gα(13) Haploinsufficiency
Heterotrimeric G proteins are critical transducers of cellular signaling. Of the four families of G proteins, the physiological function of Gα(13) is less well understood. Gα(13) gene-deleted mice die at embryonic day ∼9.5. Here, we show that heterozygous Gα(13)(+/−) mice display defects in adult an...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2785670/ https://ncbi.nlm.nih.gov/pubmed/19654325 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.025460 |
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