Suppression of Tumor Angiogenesis by Gα(13) Haploinsufficiency

Heterotrimeric G proteins are critical transducers of cellular signaling. Of the four families of G proteins, the physiological function of Gα(13) is less well understood. Gα(13) gene-deleted mice die at embryonic day ∼9.5. Here, we show that heterozygous Gα(13)(+/−) mice display defects in adult an...

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Bibliografske podrobnosti
Main Authors: Chen, Lin, Zhang, J. Jillian, Rafii, Shahin, Huang, Xin-Yun
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2009
Teme:
Mechanisms of Signal Transduction
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785670/
https://ncbi.nlm.nih.gov/pubmed/19654325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.025460
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