Insulin Is a Stronger Inducer of Insulin Resistance than Hyperglycemia in Mice with Type 1 Diabetes Mellitus (T1DM)

Subjects with type 1 diabetes mellitus (T1DM) eventually develop insulin resistance and other features of T2DM such as cardiovascular disorders. The exact mechanism has been not been completely understood. In this study, we tested the hypothesis that excessive or inappropriate exposure to insulin is...

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Bibliographic Details
Main Authors: Liu, Hui-Yu, Cao, Sophia Y., Hong, Tao, Han, Jianmin, Liu, Zhenqi, Cao, Wenhong
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2009
Subjects:
Metabolism and Bioenergetics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785638/
https://ncbi.nlm.nih.gov/pubmed/19654321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.016675
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