Acetylation of Transition Protein 2 (TP2) by KAT3B (p300) Alters Its DNA Condensation Property and Interaction with Putative Histone Chaperone NPM3

The hallmark of mammalian spermiogenesis is the dramatic chromatin remodeling process wherein the nucleosomal histones are replaced by the transition proteins TP1, TP2, and TP4. Subsequently these transition proteins are replaced by the protamines P1 and P2. Hyperacetylation of histone H4 is linked...

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Main Authors: Pradeepa, Madapura M., Nikhil, Gupta, Hari Kishore, Annavarapu, Bharath, Giriyapura N., Kundu, Tapas K., Rao, Manchanahalli R. Satyanarayana
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Transcription, Chromatin, and Epigenetics
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785624/
https://ncbi.nlm.nih.gov/pubmed/19710011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.052043
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