Inhibition of Lysine Acetyltransferase KAT3B/p300 Activity by a Naturally Occurring Hydroxynaphthoquinone, Plumbagin

Lysine acetyltransferases (KATs), p300 (KAT3B), and its close homologue CREB-binding protein (KAT3A) are probably the most widely studied KATs with well documented roles in various cellular processes. Hence, the dysfunction of p300 may result in the dysregulation of gene expression leading to the ma...

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Detalhes bibliográficos
Main Authors: Ravindra, Kodihalli C., Selvi, B. Ruthrotha, Arif, Mohammed, Reddy, B. A. Ashok, Thanuja, Gali R., Agrawal, Shipra, Pradhan, Suman Kalyan, Nagashayana, Natesh, Dasgupta, Dipak, Kundu, Tapas K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Transcription, Chromatin, and Epigenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2782038/
https://ncbi.nlm.nih.gov/pubmed/19570987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.023861
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