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Structural Basis for T Cell Alloreactivity among Three HLA-B14 and HLA-B27 Antigens

The existence of cytotoxic T cells (CTL) cross-reacting with the human major histocompatibility antigens HLA-B14 and HLA-B27 suggests that their alloreactivity could be due to presentation of shared peptides in similar binding modes by these molecules. We therefore determined the crystal structures...

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Detalhes bibliográficos
Main Authors: Kumar, Pravin, Vahedi-Faridi, Ardeschir, Saenger, Wolfram, Merino, Elena, López de Castro, José A., Uchanska-Ziegler, Barbara, Ziegler, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785609/
https://ncbi.nlm.nih.gov/pubmed/19617632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.038497
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