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Natural MHC Class I Polymorphism Controls the Pathway of Peptide Dissociation from HLA-B27 Complexes

Analysis of antigen dissociation provides insight into peptide presentation modes of folded human leukocyte antigen (HLA) molecules, which consist of a heavy chain, β(2)-microglobulin (β(2)m), and an antigenic peptide. Here we have monitored peptide-HLA interactions and peptide dissociation kinetics...

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Detalhes bibliográficos
Main Authors: Winkler, Kathrin, Winter, Anja, Rueckert, Christine, Uchanska-Ziegler, Barbara, Alexiev, Ulrike
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1989716/
https://ncbi.nlm.nih.gov/pubmed/17573425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.096602
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