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Oxidized Hemoglobin Is an Endogenous Proinflammatory Agonist That Targets Vascular Endothelial Cells

Several pathologic conditions are associated with hemolysis, i.e. release of ferrous (Fe(II)) hemoglobin from red blood cells. Oxidation of cell-free hemoglobin produces (Fe(III)) methemoglobin. More extensive oxidation produces (Fe(III)/Fe(IV) [Image: see text] O) ferryl hemoglobin. Both cell-free...

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Main Authors: Silva, Gabriela, Jeney, Viktoria, Chora, Ângelo, Larsen, Rasmus, Balla, Jozsef, Soares, Miguel P.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2009
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785591/
https://ncbi.nlm.nih.gov/pubmed/19700768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.045344
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