Regulation of the Proteasome by Neuronal Activity and Calcium/Calmodulin-dependent Protein Kinase II

Protein degradation via the ubiquitin proteasome system has been shown to regulate changes in synaptic strength that underlie multiple forms of synaptic plasticity. It is plausible, therefore, that the ubiquitin proteasome system is itself regulated by synaptic activity. By utilizing live-cell imagi...

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Détails bibliographiques
Auteurs principaux: Djakovic, Stevan N., Schwarz, Lindsay A., Barylko, Barbara, DeMartino, George N., Patrick, Gentry N.
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2009
Sujets:
Protein Synthesis, Post-Translational Modification, and Degradation
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785353/
https://ncbi.nlm.nih.gov/pubmed/19638347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.021956
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