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Structural and Molecular Mechanism for Autoprocessing of MARTX Toxin of Vibrio cholerae at Multiple Sites

The multifunctional autoprocessing repeats-in-toxin (MARTX) toxin of Vibrio cholerae causes destruction of the actin cytoskeleton by covalent cross-linking of actin and inactivation of Rho GTPases. The effector domains responsible for these activities are here shown to be independent proteins releas...

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Bibliografske podrobnosti
Main Authors: Prochazkova, Katerina, Shuvalova, Ludmilla A., Minasov, George, Voburka, Zdeněk, Anderson, Wayne F., Satchell, Karla J. F.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785344/
https://ncbi.nlm.nih.gov/pubmed/19620709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.025510
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