Thyrotropin Receptor Activation Increases Hyaluronan Production in Preadipocyte Fibroblasts: CONTRIBUTORY ROLE IN HYALURONAN ACCUMULATION IN THYROID DYSFUNCTION

The thyrotropin receptor (TSHR) is expressed during lineage-specific differentiation (e.g. adipogenesis) and is activated by TSH, thyroid-stimulating antibodies, and gain-of-function mutations (TSHR*). Comparison of gene expression profiles of nonmodified human preadipocytes (n = 4) with the paralle...

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Detalhes bibliográficos
Main Authors: Zhang, Lei, Bowen, Timothy, Grennan-Jones, Fiona, Paddon, Carol, Giles, Peter, Webber, Jason, Steadman, Robert, Ludgate, Marian
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Glycobiology and Extracellular Matrices
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785333/
https://ncbi.nlm.nih.gov/pubmed/19633293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.003616
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