EGFR is required for Colonic Tumor Promotion by Dietary Fat in the Azoxymethane/Dextran Sulfate Sodium Model: Roles of TGF-α and PTGS2

PURPOSE: Colon cancer is a major cause of cancer-deaths. Dietary factors contribute substantially to the risk of this malignancy. Western style diets promote development of azoxymethane (AOM)-induced colon cancer. While we showed that epidermal growth factor receptors (EGFR) controlled AOM tumorigen...

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Detalhes bibliográficos
Main Authors: Dougherty, Urszula, Cerasi, Dario, Taylor, Ieva, Kocherginsky, Masha, Tekin, Ummuhan, Badal, Shamiram, Aluri, Lata, Sehdev, Amikar, Cerda, Sonia, Mustafi, Reba, Delgado, Jorge, Joseph, Loren, Zhu, Hongyan, Hart, John, Threadgill, David, Fichera, Alessandro, Bissonnette, Marc
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785126/
https://ncbi.nlm.nih.gov/pubmed/19903783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-09-1678
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