Epidermal Growth Factor Receptor Signaling Is Required for Microadenoma Formation in the Mouse Azoxymethane Model of Colonic Carcinogenesis

Colonic carcinogenesis involves the progressive dysregulation of homeostatic mechanisms that control growth. The epidermal growth factor (EGF) receptor (EGFR) regulates colonocyte growth and differentiation and is overexpressed in many human colon cancers. A requirement for EGFR in colonic premalign...

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Xehetasun bibliografikoak
Egile Nagusiak: Fichera, Alessandro, Little, Nathaniel, Jagadeeswaran, Sujatha, Dougherty, Urszula, Sehdev, Amikar, Mustafi, Reba, Cerda, Sonia, Yuan, Weihua, Khare, Sharad, Tretiakova, Maria, Gong, Can, Tallerico, Michael, Cohen, Greg, Joseph, Loren, Hart, John, Turner, Jerrold R., Bissonnette, Marc
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2007
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2705749/
https://ncbi.nlm.nih.gov/pubmed/17234795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-05-3343
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