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QUANTIFICATION OF TRYPTOPHAN TRANSPORT AND METABOLISM IN LUNG TUMORS USING POSITRON EMISSION TOMOGRAPHY
RATIONALE: Abnormal tryptophan metabolism catalyzed by indoleamine 2,3-dioxygenase (IDO) may play a prominent role in tumor immuno-resistance in many tumor types, including lung tumors. The goal of this study was to evaluate in vivo kinetics of [Formula: see text] [(11)C]methyl-L-tryptophan (AMT), a...
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| Huvudupphovsmän: | , , , , , , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2009
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2784997/ https://ncbi.nlm.nih.gov/pubmed/19223408 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.108.058776 |
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