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Altered Synthesis of Cartilage-Specific Proteoglycans by Mutant Human Cartilage Oligomeric Matrix Protein

BACKGROUND: The mechanism by which mutant cartilage oligomeric matrix protein (COMP) induces a pseudoachondroplasia phenotype remains unknown, and the reason why a mutation of a minor protein of the growth plate cartilage causes total disruption of endochondral bone formation has not yet been determ...

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Bibliographic Details
Main Authors: Kwak, Yoon Hae, Roh, Jae Young, Lee, Ki Seok, Park, Hui Wan, Kim, Hyun Woo
Format: Artigo
Language:Inglês
Published: The Korean Orthopaedic Association 2009
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2784957/
https://ncbi.nlm.nih.gov/pubmed/19956474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4055/cios.2009.1.4.181
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