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Identification and Characterization of a Small Molecule Inhibitor of Formin-Mediated Actin Assembly
Formins stimulate actin filament assembly for fundamental cellular processes including division, adhesion, establishing polarity and motility. A formin inhibitor would be useful because most cells express multiple formins whose functions are not known, and because metastatic tumor formation depends...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2784894/ https://ncbi.nlm.nih.gov/pubmed/19942139 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2009.10.006 |
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