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Influence of processing-induced phase transformations on the dissolution of theophylline tablets
The object of this investigation was to evaluate the influence of (1) processing-induced decrease in drug crystallinity and (2) phase transformations during dissolution, on the per-formance of theophylline tablet formulations. Anhydrous theophylline underwent multiple transformations (anhydrate »hyd...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Springer-Verlag
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2784859/ https://ncbi.nlm.nih.gov/pubmed/15198529 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/pt050108 |
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