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Triamterene-β-cyclodextrin systems: Preparation, characterization and in vivo evaluation

The purpose of this research was to improve the solubility and therefore dissolution and bioavailability of triamterene, a poorly water soluble diuretic, by complexation with β-cyclodextrin. Triamterene has been reported to show low bioavailability after oral administration, with wide intersubject v...

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Hlavní autoři: Mukne, Alka Pravin, Nagarsenker, MS
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer-Verlag 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2784853/
https://ncbi.nlm.nih.gov/pubmed/15198540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/pt050119
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