Counting Synapses Using FIB/SEM Microscopy: A True Revolution for Ultrastructural Volume Reconstruction

The advent of transmission electron microscopy (TEM) in the 1950s represented a fundamental step in the study of neuronal circuits. The application of this technique soon led to the realization that the number of synapses changes during the course of normal life, as well as under certain pathologica...

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Autors principals: Merchán-Pérez, Angel, Rodriguez, José-Rodrigo, Alonso-Nanclares, Lidia, Schertel, Andreas, DeFelipe, Javier
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Research Foundation 2009
Matèries:
Neuroscience
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2784681/
https://ncbi.nlm.nih.gov/pubmed/19949485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/neuro.05.018.2009
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