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Interaction of Heparins and Dextran Sulfates with a Mesoscopic Protein Nanopore

A mechanism of how polyanions influence the channel formed by Staphylococcus aureus α-hemolysin is described. We demonstrate that the probability of several types of polyanions to block the ion channel depends on the presence of divalent cations and the polyanion molecular weight and concentration....

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Autores principales: Teixeira, Luciana R., Merzlyak, Petr G., Valeva, Angela, Krasilnikov, Oleg V.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Biophysical Society 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2784562/
https://ncbi.nlm.nih.gov/pubmed/19948118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.09.019
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