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Interaction of Heparins and Dextran Sulfates with a Mesoscopic Protein Nanopore

A mechanism of how polyanions influence the channel formed by Staphylococcus aureus α-hemolysin is described. We demonstrate that the probability of several types of polyanions to block the ion channel depends on the presence of divalent cations and the polyanion molecular weight and concentration....

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Detalhes bibliográficos
Main Authors: Teixeira, Luciana R., Merzlyak, Petr G., Valeva, Angela, Krasilnikov, Oleg V.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2784562/
https://ncbi.nlm.nih.gov/pubmed/19948118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.09.019
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