Electrophilic Peroxisome Proliferator–Activated Receptor-γ Ligands Have Potent Antifibrotic Effects in Human Lung Fibroblasts

Pulmonary fibrosis is a progressive scarring disease with no effective treatment. Transforming growth factor (TGF)-β is up-regulated in fibrotic diseases, where it stimulates differentiation of fibroblasts to myofibroblasts and production of excess extracellular matrix. Peroxisome proliferator–activ...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Ferguson, Heather E., Kulkarni, Ajit, Lehmann, Geniece M., Garcia-Bates, Tatiana M., Thatcher, Thomas H., Huxlin, Krystel R., Phipps, Richard P., Sime, Patricia J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Thoracic Society 2009
Schlagworte:
Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2784409/
https://ncbi.nlm.nih.gov/pubmed/19286977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2009-0006OC
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge