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Antifibrotic Actions of Peroxisome Proliferator-Activated Receptor γ Ligands in Corneal Fibroblasts Are Mediated by β-Catenin–Regulated Pathways
Wound healing after corneal injury typically involves fibrosis, with transforming growth factor β1 (TGF-β1) as one of its strongest mediators. A class of small molecules—peroxisome proliferator–activated receptor γ (PPARγ) ligands—exert potent antifibrotic effects in the cornea by blocking phosphory...
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| Vydáno v: | Am J Pathol |
|---|---|
| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Investigative Pathology
2017
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5530905/ https://ncbi.nlm.nih.gov/pubmed/28606794 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2017.04.002 |
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