Absence of Proteinase-Activated Receptor-1 Signaling in Mice Confers Protection from fMLP-Induced Goblet Cell Metaplasia

The morphological features of chronic obstructive pulmonary disease in man include emphysema and chronic bronchitis associated with mucus hypersecretion. These alterations can be induced in mice by a single intratracheal instillation of N-formyl-L-methionyl-L-leucyl-L-phenylalanine (fMLP), a chemoat...

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Huvudupphovsmän: Atzori, Luigi, Lucattelli, Monica, Scotton, Chris J., Laurent, Geoffrey J., Bartalesi, Barbara, De Cunto, Giovanna, Lunghi, Benedetta, Chambers, Rachel C., Lungarella, Giuseppe
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Thoracic Society 2009
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Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2784406/
https://ncbi.nlm.nih.gov/pubmed/19307611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2007-0386OC
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