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Absence of Proteinase-Activated Receptor-1 Signaling in Mice Confers Protection from fMLP-Induced Goblet Cell Metaplasia

The morphological features of chronic obstructive pulmonary disease in man include emphysema and chronic bronchitis associated with mucus hypersecretion. These alterations can be induced in mice by a single intratracheal instillation of N-formyl-L-methionyl-L-leucyl-L-phenylalanine (fMLP), a chemoat...

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Bibliografski detalji
Glavni autori: Atzori, Luigi, Lucattelli, Monica, Scotton, Chris J., Laurent, Geoffrey J., Bartalesi, Barbara, De Cunto, Giovanna, Lunghi, Benedetta, Chambers, Rachel C., Lungarella, Giuseppe
Format: Artigo
Jezik:Inglês
Izdano: American Thoracic Society 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2784406/
https://ncbi.nlm.nih.gov/pubmed/19307611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2007-0386OC
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