Absence of Proteinase-Activated Receptor-1 Signaling in Mice Confers Protection from fMLP-Induced Goblet Cell Metaplasia

The morphological features of chronic obstructive pulmonary disease in man include emphysema and chronic bronchitis associated with mucus hypersecretion. These alterations can be induced in mice by a single intratracheal instillation of N-formyl-L-methionyl-L-leucyl-L-phenylalanine (fMLP), a chemoat...

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Main Authors: Atzori, Luigi, Lucattelli, Monica, Scotton, Chris J., Laurent, Geoffrey J., Bartalesi, Barbara, De Cunto, Giovanna, Lunghi, Benedetta, Chambers, Rachel C., Lungarella, Giuseppe
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Thoracic Society 2009
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Articles
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2784406/
https://ncbi.nlm.nih.gov/pubmed/19307611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2007-0386OC
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