Absence of Proteinase-Activated Receptor-1 Signaling in Mice Confers Protection from fMLP-Induced Goblet Cell Metaplasia

The morphological features of chronic obstructive pulmonary disease in man include emphysema and chronic bronchitis associated with mucus hypersecretion. These alterations can be induced in mice by a single intratracheal instillation of N-formyl-L-methionyl-L-leucyl-L-phenylalanine (fMLP), a chemoat...

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Bibliographische Detailangaben
Hauptverfasser: Atzori, Luigi, Lucattelli, Monica, Scotton, Chris J., Laurent, Geoffrey J., Bartalesi, Barbara, De Cunto, Giovanna, Lunghi, Benedetta, Chambers, Rachel C., Lungarella, Giuseppe
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Thoracic Society 2009
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2784406/
https://ncbi.nlm.nih.gov/pubmed/19307611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2007-0386OC
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