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Next generation sequence analysis for mitochondrial disorders

BACKGROUND: Mitochondrial disorders can originate from mutations in one of many nuclear genes controlling the organelle function or in the mitochondrial genome (mitochondrial DNA (mtDNA)). The large numbers of potential culprit genes, together with the little guidance offered by most clinical phenot...

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Bibliografiske detaljer
Main Authors: Vasta, Valeria, Ng, Sarah B, Turner, Emily H, Shendure, Jay, Hahn, Si Houn
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2784303/
https://ncbi.nlm.nih.gov/pubmed/19852779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gm100
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