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The Toll-like Receptor 3:dsRNA signaling complex
Toll-like receptors (TLRs) recognize conserved molecular patterns in invading pathogens and trigger innate immune responses. TLR3 recognizes dsRNA, a molecular signature of most viruses via its ectodomain (ECD). The TLR3-ECD structure consists of a 23 turn coil bent into the shape of a horseshoe wit...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2784288/ https://ncbi.nlm.nih.gov/pubmed/19595807 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagrm.2009.06.005 |
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