Synthesis and Evaluation of a Thio Analogue of Duocarmycin SA

The design, synthesis, and preliminary evaluation of methyl 1,2,8,8a-tetrahydrocyclopropa[c]thieno[3,2-e]indol-4-one-6-carboxylate (CTI) derivatives are detailed representing a single atom change (NH→S) embedded in the duocarmycin SA alkylation subunit.

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Detaylı Bibliyografya
Asıl Yazarlar: MacMillan, Karen S., Lajiness, James P., Cara, Carlota Lopez, Romagnoli, Romeo, Robertson, William M., Hwang, Inkyu, Baraldi, Pier Giovanni, Boger, Dale L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2009
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2784222/
https://ncbi.nlm.nih.gov/pubmed/19879753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2009.10.063
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