TRPC channel-mediated neuroprotection by PDGF involves Pyk2/ERK/CREB pathway

Platelet-derived growth factor-BB (PDGF) has been reported to provide tropic support for neurons in the central nervous system. The protective role of PDGF on dopaminergic neurons, especially in the context of HIV-associated dementia (HAD), however, remains largely unknown. Herein we demonstrate tha...

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Bibliographic Details
Main Authors: Yao, Honghong, Peng, Fuwang, Fan, Yi, Zhu, Xuhui, Hu, Gang, Buch, Shilpa
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2783976/
https://ncbi.nlm.nih.gov/pubmed/19680266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2009.108
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