Diindolylmethane Inhibits Cervical Dysplasia, Alters Estrogen Metabolism and Enhances Immune Response in The K14-HPV16 Transgenic Mouse Model

This study was designed to establish whether 3,3′-Diindolylmethane (DIM) can inhibit cervical lesions, alter estrogen metabolism in favor of C-2 hydroxylation and enhance immune function in the K14-HPV16 transgenic mouse model. Mice were bred, genotyped, implanted with E(2) pellets (0.25mg/90 day re...

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Hlavní autoři: Sepkovic, Daniel W., Stein, Johann, Carlisle, Antoine D., Ksieski, H. Barbara, Auborn, Karen, Bradlow, H. Leon
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2783856/
https://ncbi.nlm.nih.gov/pubmed/19861518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-09-0698
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