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Abasic Site-Containing DNAzyme and Aptamer for Label-free Fluorescent Detection of Pb(2+) and Adenosine with High Sensitivity, Selectivity and Tunable Dynamic Range
An abasic site called dSpacer has been introduced into duplex regions of the 8–17 DNAzyme and adenosine aptamer for label-free fluorescent detection of Pb(2+) and adenosine, respectively. The dSpacer can bind an extrinsic fluorescent compound, 2-amino-5,6,7-trimethyl-1,8-naphthyridine (ATMND), and q...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2783749/ https://ncbi.nlm.nih.gov/pubmed/19807110 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja905854a |
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