Activation of the PI3K/AKT pathway induces urothelial carcinoma of the renal pelvis: Identification in human tumors and confirmation in animal models

Urothelial carcinoma of the renal pelvis is a deadly disease with an unclear tumorigenic mechanism. We conducted gene expression profiling on a set of human tumors of this type, and identified a PI3K/AKT activation expression signature in 76.9% (n=13) of our samples. Sequence analysis found both act...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Qian, Chao-Nan, Furge, Kyle A., Knol, Jared, Huang, Dan, Chen, Jindong, Dykema, Karl J., Kort, Eric J., Massie, Aaron, Khoo, Sok Kean, VandenBeldt, Kristin, Resau, James H., Anema, John, Kahnoski, Richard J., Morreau, Hans, Camparo, Philippe, Comperat, Eva, Sibony, Mathilde, Denoux, Yves, Molinie, Vincent, Vieillefond, Annick, Eng, Charis, Williams, Bart O., Teh, Bin Tean
פורמט: Artigo
שפה:Inglês
יצא לאור: 2009
נושאים:
Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2783739/
https://ncbi.nlm.nih.gov/pubmed/19843858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-1689
תגים: הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!

פריטים דומים